Description The tissue adhesive Histoacryl® consists of monomeric n-butyl-2-cyanoacrylate, which polymerises quickly in connection with tissue fluid. Histoacryl® is available in two colours: translucent, special for facial application, and blue, which enables an easy control over the quantity applied in different indications approved. Advantages Skin closure Wound closure in one minute Significant less pain than suture materials Effective microbial barrier Storage at room temperature High level of patient and physician satisfaction Save time and costs Only one layer is needed Histoacryl® can be used for closure of endoscopic incisions Sclerotherapy For bleeding and non-bleeding varices Combined therapy with Histoacryl® and conventional sclerosation therapy is possible Final hemostasis is achieved in >90% of cases Lower rebleeding rate than with band ligation Mesh fixation Non-invasive method reported to be better tolerated by the patient than traditional fixation methods Stand-alone fixation method in different hernia repair techniques Comparable recurrence rate than with traditional fixation methods Low intra- and postoperative morbidity Reduced risk of post-operative chronic pain compared to traditional fixation methods Decreased surgery time compared to traditional fixation methods Good biocompatibility and in vivo tolerance Indication Skin Closure: Closure of skin wounds without tension (including clean surgical incisions and incisions from minimally invasive surgery), and simple, thoroughly cleansed, trauma-induced lacerations. Sclerotherapy: Sclerotherapy of large oesophageal or fundal varices. Mesh fixation: Fixation of hernia meshes, especially in inguinal hernia surgery.
